Scientific Director - S.Yu. Savytsky
The Department of Radioisotopic Research Methods
The department was founded in 1980.
The main directions of research:
- the introduction into practice and perfection of radionuclide methods to increase their informational value in the diagnosis of cardiovascular diseases.
- the elaboration of criteria for the assessment of neurohumoral regulation with the aim to study the pathogenesis of main cardiovascular diseases and for selection of the right treatment.
The optimal complex of parameters of the radionuclide ventriculography for the assessment of left ventricular total and local contraction and relaxation has been designed.
The main determinants of the neurohumoral regulation in destabilization of the coronary disease have been identified. The role of the opioid peptides, the activity of hypophysial-adrenal complex and “weak T3” syndrome in acute myocardial infarction was studied. Examination of condition of the cyclic nucleotide system and representatives of endothelin family in early post-infarction stenocardia in the dynamics of patient observation after aortal-coronary stunt and in arterial hypertension was conducted.
At the department there are widely used the scintigraphy of myocardium, thyroid gland, liver, kidneys, as well as angio-, encephalo- and osteoscintigraphy. Radioimmunological methods have been introduced which allow to determine biologically active substances (prostanoids, components of renin-angiotensin-aldosterone system, atrial natriuretic peptide, opioid peptides, thyroid and calcium – regulating hormones and others). The department is equipped with gamma camera, computer radiometer and osteodensitometer.
In the last 10 years 300 scientific works were published, including 93 abroad; 2 doctorate theses in medicine were defended on the base of results of investigation carried out at the department, 20 candidate’s and doctor’s degrees in medicine were given to the scientists of the department; 9 inventions patented abroad.
The main directions of research:
- the introduction into practice and perfection of radionuclide methods to increase their informational value in the diagnosis of cardiovascular diseases.
- the elaboration of criteria for the assessment of neurohumoral regulation with the aim to study the pathogenesis of main cardiovascular diseases and for selection of the right treatment.
The optimal complex of parameters of the radionuclide ventriculography for the assessment of left ventricular total and local contraction and relaxation has been designed.
The main determinants of the neurohumoral regulation in destabilization of the coronary disease have been identified. The role of the opioid peptides, the activity of hypophysial-adrenal complex and “weak T3” syndrome in acute myocardial infarction was studied. Examination of condition of the cyclic nucleotide system and representatives of endothelin family in early post-infarction stenocardia in the dynamics of patient observation after aortal-coronary stunt and in arterial hypertension was conducted.
At the department there are widely used the scintigraphy of myocardium, thyroid gland, liver, kidneys, as well as angio-, encephalo- and osteoscintigraphy. Radioimmunological methods have been introduced which allow to determine biologically active substances (prostanoids, components of renin-angiotensin-aldosterone system, atrial natriuretic peptide, opioid peptides, thyroid and calcium – regulating hormones and others). The department is equipped with gamma camera, computer radiometer and osteodensitometer.
In the last 10 years 300 scientific works were published, including 93 abroad; 2 doctorate theses in medicine were defended on the base of results of investigation carried out at the department, 20 candidate’s and doctor’s degrees in medicine were given to the scientists of the department; 9 inventions patented abroad.